{"id":1666,"date":"2015-03-25T22:18:22","date_gmt":"2015-03-25T21:18:22","guid":{"rendered":"http:\/\/www.epitype.de\/?page_id=1666&#038;lang=en"},"modified":"2015-11-13T00:06:44","modified_gmt":"2015-11-12T23:06:44","slug":"cervical-cancer","status":"publish","type":"page","link":"https:\/\/www.epitype.de\/en\/information-for-patients\/cervical-cancer\/","title":{"rendered":"Cervical cancer"},"content":{"rendered":"\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_heading-9d3719e4ef1f2508a458878141ff566c\">\n#top .av-special-heading.av-av_heading-9d3719e4ef1f2508a458878141ff566c{\npadding-bottom:25px;\n}\nbody .av-special-heading.av-av_heading-9d3719e4ef1f2508a458878141ff566c .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-av_heading-9d3719e4ef1f2508a458878141ff566c .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-av_heading-9d3719e4ef1f2508a458878141ff566c av-special-heading-h1 blockquote modern-quote  avia-builder-el-0  el_before_av_one_half  avia-builder-el-first '><h1 class='av-special-heading-tag '  itemprop=\"headline\"  >Cervical cancer<\/h1><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n<div class=\"flex_column av_one_half  flex_column_div av-zero-column-padding first  avia-builder-el-1  el_after_av_heading  el_before_av_one_half  \" style='border-radius:0px; '><section  class='av_textblock_section av-av_textblock-0366cc7376be6c9e82a3e9cc8987b64f '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>With more than 500,000 new cases and more than 260,000 deaths reported annually, cervical cancer is still among the most common cancers in women worldwide. In Europe and North America, 67,000 and 14,000 new cases and 28,000 and 7,100 deaths were recorded, respectively, in 2012. On the other hand, in Europe and North America ca 7 million women annually receive an abnormal Pap smear result requiring medical follow-up when getting screened for cervical cancer. Only few of these women have a cervical disease deserving treatment.<\/p>\n<\/div><\/section><\/div><div class=\"flex_column av_one_half  flex_column_div av-zero-column-padding   avia-builder-el-3  el_after_av_one_half  el_before_av_hr  \" style='border-radius:0px; '><section  class='av_textblock_section av-av_textblock-0366cc7376be6c9e82a3e9cc8987b64f '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p><a href=\"http:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/Tumorzellen_Abstrich.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-900\" src=\"http:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/Tumorzellen_Abstrich-300x122.png\" alt=\"Tumorzellen_Abstrich\" width=\"300\" height=\"122\" srcset=\"https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/Tumorzellen_Abstrich-300x122.png 300w, https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/Tumorzellen_Abstrich-450x182.png 450w, https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/Tumorzellen_Abstrich.png 486w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p><em>Microscopy of Pap smears from (left) a healthy patient and (right) a patient with high-grade dysplasia CIN3. Not always the small tumor cells can be observed so clearly.<\/em><\/p>\n<\/div><\/section><\/div><div  class='hr av-av_hr-dcd2069817a0e3d34ae04cad8f3443c7 hr-default  avia-builder-el-5  el_after_av_one_half  el_before_av_heading '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div><\/p>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_heading-48252dc10a8bd2f815fd3d10ecee94ed\">\n#top .av-special-heading.av-av_heading-48252dc10a8bd2f815fd3d10ecee94ed{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-av_heading-48252dc10a8bd2f815fd3d10ecee94ed .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-av_heading-48252dc10a8bd2f815fd3d10ecee94ed .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-av_heading-48252dc10a8bd2f815fd3d10ecee94ed av-special-heading-h3 blockquote modern-quote  avia-builder-el-6  el_after_av_hr  el_before_av_one_half '><h3 class='av-special-heading-tag '  itemprop=\"headline\"  >Human Papillomaviruses \u2013 causative agents of cervical cancer<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n<div class=\"flex_column av_one_half  flex_column_div av-zero-column-padding first  avia-builder-el-7  el_after_av_heading  el_before_av_one_half  \" style='border-radius:0px; '><section  class='av_textblock_section av-av_textblock-0366cc7376be6c9e82a3e9cc8987b64f '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>Cervical cancer alsmost always is evoked by infection with so-called human papillomaviruses (HPV). HPV infecten is supposed to be the the most common sexually transmitted infection. In most cases the infection does not cause any symptoms, and it is cleared within 1-2 years.<\/p>\n<p>More than 150 HPV types are characterized to date. 14 of these are high-risk types, since persistent infection with any of these types may lead to cancer.<\/p>\n<p>Since 2007, vaccinations are available against the two HPV types which are most frequently found in cervical cancer tissue. Therefore, participation in screening programs is still required.<\/p>\n<\/div><\/section><\/div><div class=\"flex_column av_one_half  flex_column_div av-zero-column-padding   avia-builder-el-9  el_after_av_one_half  el_before_av_hr  \" style='border-radius:0px; '><section  class='av_textblock_section av-av_textblock-0366cc7376be6c9e82a3e9cc8987b64f '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p><a href=\"http:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/Zervix.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-916 aligncenter\" src=\"http:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/Zervix-300x216.jpg\" alt=\"Zervix\" width=\"349\" height=\"251\" srcset=\"https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/Zervix-300x216.jpg 300w, https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/Zervix.jpg 879w, https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/Zervix-705x508.jpg 705w, https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/Zervix-450x324.jpg 450w\" sizes=\"auto, (max-width: 349px) 100vw, 349px\" \/><\/a><\/p>\n<p><em>The so-called transformation zone is located at the portio and cervix. In case of small lesions, HPV may enter the cells and persist.<\/em><\/p>\n<\/div><\/section><\/div><div  class='hr av-av_hr-dcd2069817a0e3d34ae04cad8f3443c7 hr-default  avia-builder-el-11  el_after_av_one_half  el_before_av_heading '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div><\/p>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_heading-2a598847b606b7c7f77ede3c7f6058df\">\n#top .av-special-heading.av-av_heading-2a598847b606b7c7f77ede3c7f6058df{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-av_heading-2a598847b606b7c7f77ede3c7f6058df .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-av_heading-2a598847b606b7c7f77ede3c7f6058df .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-av_heading-2a598847b606b7c7f77ede3c7f6058df av-special-heading-h3 blockquote modern-quote  avia-builder-el-12  el_after_av_hr  el_before_av_one_half '><h3 class='av-special-heading-tag '  itemprop=\"headline\"  >From HPV infection to cancer \u2013 a rare event<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n<div class=\"flex_column av_one_half  flex_column_div av-zero-column-padding first  avia-builder-el-13  el_after_av_heading  el_before_av_one_half  \" style='border-radius:0px; '><section  class='av_textblock_section av-av_textblock-0366cc7376be6c9e82a3e9cc8987b64f '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>It may take many years from infection with HPV to carcinogenesis. Therefore the chance to detect the cancer or it\u2019s precursors early enough, is quite high. Cervical cancer develops slowly, and several precancerous stages, so-called dysplasias or neoplasias, can be diagnosed. However, only few of these dysplasias progress to cancer, most of them heal spontaneously.<\/p>\n<p>GynTect offers the chance to detect those dysplasias that have a high potential to progress to cancer. In all other cases, a strategy of watchful waiting may help to avoid surgery. This is of prime importance especially for women in their reproductive age: complications during pregnancy such as higher risk for preterm birth or even perinatal death may be a consequence of surgery.<\/p>\n<\/div><\/section><\/div><div class=\"flex_column av_one_half  flex_column_div av-zero-column-padding   avia-builder-el-15  el_after_av_one_half  avia-builder-el-last  \" style='border-radius:0px; '><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_image-d6ea79104b8e8824ec82e4ee570a52ae\">\n.avia-image-container.av-av_image-d6ea79104b8e8824ec82e4ee570a52ae img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-av_image-d6ea79104b8e8824ec82e4ee570a52ae .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-av_image-d6ea79104b8e8824ec82e4ee570a52ae av-styling-no-styling av-hover-grow av-img-linked avia-align-center  avia-builder-el-16  el_before_av_textblock  avia-builder-el-first '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><a href=\"https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/CIN_development_mittel-1030x610.jpg\" data-srcset=\"https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/CIN_development_mittel-1030x610.jpg 1030w, https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/CIN_development_mittel-300x178.jpg 300w, https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/CIN_development_mittel-1500x889.jpg 1500w, https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/CIN_development_mittel-705x418.jpg 705w, https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/CIN_development_mittel-450x267.jpg 450w, https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/CIN_development_mittel.jpg 1772w\" data-sizes=\"(max-width: 1030px) 100vw, 1030px\" class='avia_image '  aria-label='CIN_development_mittel'><img decoding=\"async\" fetchpriority=\"high\" class='wp-image-915 avia-img-lazy-loading-not-915 avia_image ' src=\"https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/CIN_development_mittel-300x178.jpg\" alt='' title='CIN_development_mittel'  height=\"178\" width=\"300\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/CIN_development_mittel-300x178.jpg 300w, https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/CIN_development_mittel-1030x610.jpg 1030w, https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/CIN_development_mittel-1500x889.jpg 1500w, https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/CIN_development_mittel-705x418.jpg 705w, https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/CIN_development_mittel-450x267.jpg 450w, https:\/\/www.epitype.de\/wp-content\/uploads\/2015\/08\/CIN_development_mittel.jpg 1772w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-av_textblock-0366cc7376be6c9e82a3e9cc8987b64f '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p><em>Cellular changes during carcinogenesis. In early stages only few neoplastic cells are found in the basal cell layer, whereas in later stages such as CIN3 or carcinoma in situ all cell layers are affected.<\/em><\/p>\n<\/div><\/section><\/p><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":10,"featured_media":0,"parent":1664,"menu_order":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1666","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Cervical cancer - Epitype GmbH<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.epitype.de\/en\/information-for-patients\/cervical-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cervical cancer - 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